Functional Water - Kaqun Important Essay about the Naure of Kaqun

Dr. Iván Szalkai: Functional waters – the Kaqun water
Nowadays we hear with increasing frequency about therapeutic products, or agents claimed to be special, „miraculous”. These wonderworking agents often fail in scientific verification tests, however the explanation of their effect can often be found in areas with which we doctors are less familiar. For a long time this was the case with oxygen water. One of the reasons for the lack of explanation was the mechanism of producing oxygen water, as it is possible to find water, which was simply charged with oxygen – with a technology similar to soda water, where CO2 gas is absorbed by the water. There is also the water treated with ozone; but characteristically, in this case when the pressure decreases oxygen will soon be discharged from the water therefore it is impossible to detect its effect.
One type of water with increased oxygen level is the Kaqun water. The healing effect of Kaqun water is confirmed by several facts based on experience and experiments, but there is also doubt among the professionals, how can this water heal.
Experiments trace back the healing effects of the water to the following factors:
1. The water as a substance with special properties
2. Effects of dissolved oxygen in water
3. The change of the redox system in the body due to the water treatment
4. The alkaline effect of Kaqun water
Kaqun technology
The Kaqun water conversion technology is patented. In brief, the filtered water is led through an electric and magnetic field operating at a given frequency, then the water stays between catalyzers for a given time. Due to the treatment the following changes occur:
- The large water clusters break up and small, more stable clusters are formed consisting of 6-9 molecules
- Due to the electric field, the oxygen which is released builds into the small clusters
- The oxygen and part of the hydrogen form OH radical to alkalize the water
However, methods have been developed recently which change the structure of the water and thus it became possible to increase the oxygen content of the water for long periods.
But what really is water? We know it, we drink it, and it flows from the tap and is slowly becoming one of the most valuable assets. We are used to water being here for us; there is no life without it, and it is a significant component of the biologic structures. We know that its structure is H2O. We know that it freezes at 0 degrees and boils at 100 degrees, and one of its specificities is that it is denser in 4 degrees than at 0 degrees, (did we ever wonder why?).
However, comparing it with other, similar molecules containing 2 H atoms (H2S, H2Se, H2Te), we find that based on its molecular weight it should boil at -100 degrees. In the sixth column of the periodic table of elements – where the oxygen is – the boil degree is basically higher, but water stands out even among these. The structure of the water, which is called cluster, is responsible for this phenomenon. That’s why the formula of the water is not H2O, but H2nOn. Its basic structure is tetrahedron (4-water molecules form the structure H8O4). These tetrahedrons make up the clusters consisting of several hundred molecules. Liquid water contains individual molecules as well as small and large clusters. These formations are continuously changing, decomposing and building, but about 10% stay stable. These formations can store other molecules inside their inner space and then slowly release them. Compared to the biochemical processes these clusters remain stable for long (msec) periods. Depending on how the dipole structured water molecules are aligned on the external shell of the cluster, they can have + or – charge, that is they are either acid or alkaline. Whether the cluster can penetrate the cell membrane or it remains in the intercellular space depends on its size. Small clusters consisting of 6-
8 water molecules can penetrate the cell wall. The water without clusters is considered „dead” water. Water penetrates the cell membrane with the help of “transport” proteins. The transport protein is a protein which is spirally coiled and the negative charged amino acids are located on the outer side where they form a channel, where the dipole water (small water clusters consisting of 6-9 water molecules) and the bound (dissolved within) substances can penetrate the cell membrane. The osmotic pressure also plays a part in the penetration since inside the cell thanks to substances dissolved the osmotic pressure 300 mosm/l, (isotonicity 280 mosm/l), which is higher than the osmotic pressure of the extracellular field. The filtering role of the membrane cell is represented by, that the ph-value is 6.8 inside the cell, while it is 7.3-7.4 in the field outside the cell. The strong negative charged sialic acid on the surface of the cell can secure the wet shell of the cell wall with Van der Waals bonds.
The forming of clusters is allowed by the dipole characteristics. The oxygen side is negative charged the hydrogen atoms side is positive charged. The electric difference allows for H-O bridges to be formed between the water molecules, whose distance is greater but their bond strength is smaller than the strength of the H-O bond inside the molecule. These bonds form the basic tetrahedron structure of the water. The variability of the cluster structure creates the crystal structure of the water. The frozen water is solid crystal, which when melted transforms to a liquid crystal. As the temperature increases, so does this cluster structure shifts towards the individual molecules – the clusters break up and the individual water molecules become gas phase. The ratio and form of the clusters are influenced by several factors.
The speciality of Kaqun water is that in the course of the structural change oxygen atoms are freed from their bonds and are stored inside the small clusters, and the large clusters break down to sizes still able to retain the oxygen within them but are also able to penetrate the cell membrane.
The other form of the water is not the spherical cluster but the strand shaped polymer structure. This structure is able to string up the ring shaped molecules (proteins, hormones, carbohydrates) enabling chemical reaction, „exchange of information” to take place between them. The exchange of information between cells has been discovered as the result of research carried out in the last decades and can
be connected to the biophotons. These photons are released in the course of chemical reactions and affect the way the cells function.
Polymerization can be electron donor and electron acceptor, thus taking part in the “fight” for the free electrons inside the body. One of the mechanisms which start polymerization can be connected to the presence of Fe2 and hyperoxid (Fenton reaction).
Fe2+ + H2O2 = Fe3+ + OH- + OH*
The created radicals start the polymerization of the water.
Water polymers have a special characteristic, the modification velocity of the polymers changes when irradiated with external frequency (sound, light). When exposed to light the spontaneous vibration frequence of the polymer increases. The evaluation of this phenomenon goes a long way and is present in the explanation of the effect of other therapies too, like sound, laser, infrared radiation, infrasound, Tibetan bells, magnetic therapy and mobile phones.
The water clusters explain the physical characteristics of the water, like the special surface tension, wherein due to the van der Waals energies the surface of the liquid can be pressured to some degree, the inwardly energy of the surface molecules exceed the outwardly forces caused by the movement of the molecules. This does not only have significance in case of water striders, but also in the penetration of substances in liquids through the surface of the skin, in this case the transport of dissolved oxygen into the body.
Researches separate the biological water (within the cell) from other water. The dipole structure of the water allows the bonding of hydrophile and hydrophobe proteins (macromolecules) within the cell, establishing enzyme reactions.
Kaqun water contains 18-20 mg oxygen per litre, which is 6-8 times more then the average oxygen content. The oxygen retention capacity of the water is such that the oxygen content of Kaqun water left in the open for 5 days decreases by 6.5% only-
Oxygen. Oxygen is the other corner stone of life, besides water. There is no life without oxygen, oxygen is such a nutrient to cells, which is a terminal electron acceptor in oxidative phosphorylation, but oxygen is also a very strong poison, and the body is only able to balance the effect of oxygen through a very complex regulating (redox) system. In an environment where there is a shortage or an excess of oxygen there is a change in the functioning of many cells.
The treatment with oxygen dissolved in water was developed by a German professor, Otto Warburg for the supplementary treatment of patients suffering from silicosis. By now it is well known that oxygen dissolved in water in suitable form improves the oxygen supply of the tissues, first of all naturally around the entry-absorption site (skin, alimentary tract, liver), but due to the stability of the clusters it reaches further by the blood. Tests carried out in different tumour cell lines showed a 50-100% decrease in the number of tumour cells. The effect is not linear with the oxygen concentration, and is only present in Kaqun water, and not in boiled water (boiling breaks down the cluster structure).
In today’s oxygen treatment the hyperbaric oxygen therapy is similar to the Kaqun water. Good results can be reached with long-term treatment in case of skin ulcers, people with carbon monoxide poisoning. During the treatment we can see through indicators the decrease of oxidative stress and inflammation. One side-effect of the hyperbaric oxygen therapy, spontaneous fracture does not occur in case of water treatments. Tissue hypoxia plays a role in the development of stroke, myocardial heart attack, diabetes and tumors.
The growth of tumour cells accelerates under a partial oxygen pressure of 7 Hgmm. When the level of oxygen falls below 2.5 Hgmm, the tumour cells loose their sensitivity to radiation, cytostaticum, and photodynamic treatment. During the measurement of tumor oxygenation it became proven that low (5-20 Hgmm partial pressure) significantly increases when inhaling high oxygen content air mixture. On the periphery of the tumor this can reach up to 160 Hgmm, while on the interior of the tumor 40-60 Hgmm (Kenneth 2007).
During the examination we were getting results that mice were put from hypoxic atmosphere to normal oxygen concentration (from 10% to 21%) the rate of
lymphoma development increased. In the case of Kaqun water – as we saw it – other processes are dominating.
Effects on free radicals, effects of oxidative stress
The oxygen in the body plays a very important electron-transfer role. The process: O’-> O2 ->O3 -> OH- ->H2O2 ->H2nOn
Cellular metabolism contain predominantly such redox processes, where even under physiological conditions oxygen with strong oxidative properties (Reactive Oxygen Species, ROS), nitrogen (Reactive Nitrogen Species, RNS) substances. They include free radicals with one or more unpaired electrons on their external electron shell, such as hydroxyl radical, superoxide radical, nitric oxid radical, lipid peroxyl radical; and molecules with highly reactive properties, such as hydrogen peroxide or hypochlorous acid. Due to the Kaqun water, the amount of free radicals in the body increases, which start biological processes representing dangerous signals for the body.
Though free radicals and reactive compounds play an important role as necessary signals in a given concentration and location for the physiological functioning of the cell (Droge, 2002). Thanks to their great reactive properties, they play a regulatory role in the signal transduction pathways, since getting into interaction with signalling molecules or enzyme proteins they can influence their functions.
Nowadays more and more studies confirm the signalling role of the redox system. The redox signal triggers specific regulatory processes (e.g. apoptosis at cellular level, vasodilation at tissue level, etc.). Redox processes have a role and place in the operation of the body, they can’t be considered as clearly negative participants, although they play a role in many lesions and diseases. Nowadays the regulatory role of free radicals is considered more primary as their pathological role, which is not about free radicals, but about the pathology, exhaustion of the body’s control system. The oxygen molecule is not dangerous, but during transformation with electron uptake free radicals are developed and these have harmful effects as well.
The life span of free radicals in vivo 10-7, 10-4 sec which enables them to act as signals and exert their effects not only at the place of creation but further away as well. The physiological location of the creation and control of free radicals is in the cell mitochondrion. Here the continuously created free radicals are neutralized by the superoxide dismutase enzyme. In the presence of iron or copper ions it is very aggressive. OH radical is created, which stays for 10-9 sec. No enzyme is able neutralize this (Fenton-reaction). As we have seen it, this reaction also has a role in water polymerization. The control of the body takes place in the earlier, peroxide phase.
Should the balance of the pro-oxidant and anti-oxidant system be upset degenerative diseases begin; this is called oxidative stress.
The living cells, as electrical systems continuously create and maintain an extreme, complex, 3-dimensional electric, i.e. redox pattern. The most efficient and quick physiological (and pathological) control is done by reactive oxygen and nitrogen derivatives. In the aerob cells the coordinated mitochondrial network consumes 90% of the oxygen used, securing the energy provided by ATP for cellular processes. This dynamic mitochondrial energy and the redox system change from moment-to-moment depending on the intra- and extracellular signs. When the oxygen is few compared to the current energy demand of the cell (reduced oxygen supply or increased energy demand) the coordinated intracellular mitochondrial network issues a hypoxic redox signal with the increased ROS emittance. The increased ROS emittance, as a secondary messenger system induces a coordinated complex response with redox-sensitive factors and molecules.
The oxidative processes in the body are bound to two compounds, ROS and RNS group. The RNS enzyme has three different isoforms. The neuronal nRNS (in central and peripheral neurons) and endothelial eRNS (mainly in endothelial cells) which are continuously expressed calcium- and calmodulin dependant enzymes. The inducible iRNS are created in immune cells and several other cell types. The transcriptional activation of iRNS can be caused by endogenous mediators (chemokines, cytokines) or exogenous factors (bacterial toxins, viral infections, allergens, ozone, hypoxia, tumors etc.)
The ROS effects in the signal transduction pathways can be divided into 4 main groups (Waldeck et al., 2009.):
- enhancing the IC-concentration of certain ions (e.g. Ca2+) triggers contraction and cell migration
- activating certain transcription factors (AP-1, NFκB, HIF-1) induces inflammation
- the matrix affecting metalloproteinase can modify the proteins of the extracellular matrix;
- reversibly inactivates such protein tyrosine-phosphatase such as the mitogen-activated protein kinase (MAPK) which represent an important signal transduction pathway ultimately activate transcription factors (e.g. c-myc, p38) which regulate apoptosis, cell growth and differentiation
The phagocyte enhancing effect of Kaqun water can be lead to the increased creation of free radicals, their main source is the NADPH oxidase (NOX). The superoxide-anion radical has an important defensive role in destroying pathogens which are created in large quantities towards the extracellular field. In the macrophage cells, the NADPH-oxidase as membrane-bound enzyme.
The mitochondrion’s role
The mitochondrion is the energy-creating organ of the cell, oxygen consumption and thus, free electron production.
The mitochondrion plays an important role, through Ca2+ metabolism to release the signal for starting apoptosis or cell growth. In the mitochondrion both the ROS and NOS system are present. The main igniters of mitochondrial ROS production are the inner membrane potential, Ca2+, O tension, NO and nutrient availability.
This ROS/RNS induced and regulated responses can influence gene expression, apoptosis, cell growth, cell adhesion, chemotaxis, protein-protein interactions, enzymatic functions, angiogenesis, immune processes, inflammatory
processes, Ca2+ homeostasis, ion channels and many other processes. During hyperbaric oxygen therapy the increase in the NO level showed paralellism with the healing rate of chronic ulcers.
Within experimental conditions, in the course of in vitro tests maximum reactive oxygen radical concentration in oxygenated Kaqun water can be achieved in 10 seconds. This reaction occurs in the same way in the cell system too, as both the generation of peroxidase from molecular oxygen and the oxidation of the substrate take place in the cell wall while reactive oxygen is produced. NADH also participates in the reaction. When the system is sound, the processes are in equilibrium. It is known that the absence of reactive oxygen radicals is just as problematic as their overproduction, which causes oxidative stress. The very fast increase of reactive oxygen measured in the in-vitro system supports the assumption that the feeding of oxygenated water in the required quantities will lead to the fast production of larger quantities of OH radicals in the Fenton (Haber-Weiss) reaction also within in-vitro circumstances. It is a known fact that the intracellular state, the reactive oxygen radicals (ROS) play an important role in apoptosis. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are important signal systems in the intra and intercellular communication and in the conservation of the redox-homeostasis. This ROS/RNS induced and regulated response is able to influence gene expression, apoptosis, cell growth, cell adhesion, chemotaxis, protein–protein interactions and the enzymatic functions, angiogenesis, immune processes, inflammation processes, Ca2+ homeostasis, ion channels and many other processes.
The appearance of ROS in the lymphoid cells activates a transcription enzyme, which is an important factor in the cellular level oxidative stress. The ROS and RNS activation in the cell influence the degradation of incorrectly winded protein molecules, affects the operation of phospholipids and these materials are also important elements in signal creation as well.
The role of free radicals in the nervous system
ROS and RNS also operate as a signal for the nervous system, they have a role in the neural signalling processes, in the development of nervous system plasticity and memory. The NO is such a free radical molecule which is able to freeéy diffundate through the cell membrane and can act as a neurotransmitter,
neuromodulator and signalling molecule. It regulates neurotransmitter emission and through this way the synaptic activity and can regulate the excitability of midbrain dopamine neurons. However, neurotransmitters also have antioxidant and free radical catching properties, thus they regulate neurotransmission and the protective effects toward neurons.
The intake of Kaqun water creates a reactive radical peak (–√OH, O2− and H2O2) at the moment of consumption which with the above mechanism enhances the effect of free radicals and apoptosis, as well as the stimulation of the immune system on the one hand, and also provokes the body’s own anti-oxidant system. This wave of reactive radical production represents a strong apoptotic stimulus.
The body’s protection against oxidative stress is represented on three levels:
1. Antioxidant enzymes
2. Endogenous non-enzymatic antioxidant
3. Exogenous antioxidants (taken with food). It should be noted that the trace elements do not possess antioxidant effects, but also necessary for building the antioxidant enzymes of the body.
This is one of many and repeated proofs that there is a dynamic equilibrium in the body, and with our therapy, we must achieve the conservation of this equilibrium, therefore the one-sided blocking treatment may not be expedient.
Role of alkaline effect
Kaqun water is slightly alkaline, ph 7.6-8. The chemical effect on the inside of the cell is slightly acidic, the intracellular field slightly alkaline. The metabolites of the body are basically acidic which are excreted through kidneys, feces and skin.
Urine: between 4.5-8.5, depending on diet
Stool: 5.5, depending on diet
Sweat-skin: 4.5-5.5
The body also uses breathing (reduction of CO2 levels) and body fat to expel the unnecessary acidic substances. One task of the body fat is to store the acidic metabolites.
The consumption of slightly alkaline Kaqun water promotes the neutralization of the created acidic substances, and during bath by neutralizing the acids on the skin to increase their excretion. The viability of tumor cells decrease in alkaline medium.
Results of other measurements with Kaqun water:
1. Muscular power increased after drinking water. Reaction time decreases by several msecs. This measurement showed the increase in the performance of the muscular system due to the consumption of Kaqun water.
2. The oxygen saturation of the blood increased by 1.2% after drinking water. The average cardiac stress measured with the Vocardio device decreased from 22 to 16 (improved), the pulse rate decreased. This measurement shows the reaction capacity of the cardiac muscles to load. Blood pressure decreased by 2%, the result of the Rosenberg test improved. (Semmelweis University, Faculty of Physical Education and Sports Sciences)
3. Cardio-vascular diseases (tests of Dr. György Zeltner):
a. In the case of patients suffering from angina the need of taking nitrates decreased in 75% of the cases, while 41% stopped taking nitrates altogether.
b. In the case of atrial fibrillation, the rhythm became normal.
c. TIA, VBI improved by 80% after drinking water
d. In the case of peripheral obliterative vascular disease walking distance increased by 85% and for 25% of leg ulcers were also cured.
e. 60% of varicose leg ulcers were cured during Kaqun bath.
4. Kaqun water bath has the effect of improving skin diseases (virus, bacteria, fungus), and ulcers (varicose, angiostenotic, diabetic) improve or disappear completely. Verruca seborhoica flattens, their numbers decrease.
5. In the case of traumatic injuries epithelisation accelerates, burnt skin (radiation, thermal burns) heals without or with minimal scarring.
6. In the case of severe physical load Kaqun water decreases fatigue (long distance driving)
Use/application:
Kaqun water is used/applied in three forms.
1. Consumption of Kaqun water; in the case of preventive and conservation treatment the dose should be ½ l per day, in the case of therapy 1.5 l per day distributed throughout the day. In this case, the effect will become apparent after absorption in the alimentary tract, and the treatment is used in the case of diseases of internal organs, organs further from the skin and diseases of the alimentary tract.
2. Bathing in Kaqun water. The duration of the bath should be 50 minutes, 1-3 baths can be taken per day depending on the seriousness of the disease. It is recommended principally for diseases connoted with the skin or close to it but it is useful in other cases too. The duration of the bath cure should be two weeks, which can be continued after a pause. This should be determined according to the condition of the patient and the speed of healing
3. The use of oxy gel, which ensures long-term oxygen effect in the case of ulcers.
Availability of the treatment:
The Kaqun treatment site operates at the basement of the Semmelweis Hospital surgery. Appointment: 06-20-2056789. Professional questions: Dr. Zoltán Hegedűs
Literature:
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